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  National Institute of Nutrition
Jamai-Osmania PO
Hyderabad-500 007, India.
Ph No: #+914027197200
Email: nin@ninindia.org ,
             nin@ap.nic.in
FAX: 04027019074
Grams: NUTRITION
 

 
Name: Dr. SUDHAKAR REDDY VADDE
Designation : Scientist B
Division: BIOCHEMISTRY
Phone: +91-40-27197293
E-mail: sudhakarnin@gmail.com
 

Brief Profile:

With an M.Sc. degree in Genetics from Osmania University in 2008 and PhD, Biochemistry from Osmania University in 2015, he went on to do his postdoctoral research at the Cincinnati Children’s Hospital & Medical Center (CCHMC) in the area of Cystic Fibrosis. Then, he joined the Institute in November 2016 as Scientist-B. His research interests include understanding the impact of dietary factors and functional foods on metabolic disorders such as diabetes and obesity. Besides, he is also working to understand the role of chaperones, and protein quality control in diabetes and obesity. He was awarded JRFs from ICMR, UGC and National-PDF, DR. D.S. Kotari-Post Doctoral Fellowship (PDF), PDF from CCHMC.

 
Total publications : 11
Publications in last 10 years
  1. Reddy, VS., Raghu, G., Reddy, SS., Kumar, PA., Suryanarayana, P., & Reddy, GB. Response of Small Heat Shock Proteins in diabetic rat retina. Invest Ophthalmol Vis Sci, 2013 Nov 19;54(12):7674-82 (PMID-24159092)
  2. Reddy, VS., Kumar, CU., & Reddy, GB. Effect of Chronic Hyperglycemia on crystallin levels in rat lens. Biochem Biophys Res Commun, 2014 Apr 4; 446(2):602-7. (PMID-24632206).
  3. Reddy, VS., Kumar, CU., Raghu, G., & Reddy, GB. Expression and Induction of Small Heat Shock Proteins in rat heart under chronic hyperglycemic conditions. Arch Biochem Biophys. 2014 Sep 15; 558:1-9. (PMID-24950024)
  4. Reddy, VS., & Reddy, GB. Emerging role for αB-crystallin as a therapeutic agent: pros and cons. Curr Mol Med, 2015; 15(1):47-61. (PMID-25601468)
  5. Reddy, VS., Jakhotia, S., Reddy, PY., &Reddy, GB. Hyperglycemia induced expression, phosphorylation, and translocation of αB-crystallin in rat skeletal muscle. IUBMB Life, 2015 Apr; 67(4):291-9. (PMID-25900025)
  6. Reddy, VS., & Reddy, GB. Role of crystallins in diabetic complications. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):269-77 (PMID-25988654).
  7. Vakdevi, V.,Reddy, VS.,Srinivas, PNBS., Mueller, NH., Bhagyalaxmi, SG., Padma,T., Petrash, JM., &     Reddy, GB.Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: Molecular basis for early onset of age-related cataract. FEBS letters, 2011 Dec 15; 585(24):3884-9. (PMID-22085609).
  8. Reddy, SS., Shruthi, K., Reddy, VS., Raghu, G., Suryanarayana, P., Giridhiran, N., & Reddy, GB. Altered ubiquitin proteasome system leads to neuronal cell death in a spontaneous obese rat model. Biochim Biophys Acta, 2014 Sep;1840(9):2924-34. (PMID-24949983)
  9. Shrivastava, S., Jeengar, MK., Reddy, VS., Reddy, GB.,& Naidu, VG. Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways.Exp Mol Pathol, 2015 Jun;98(3):313-27 (PMID-25818165)
  10. Moon, C., Zhang, W., Sundaram, N., Yarlagadda, S., Reddy, VS., Arora, K., Helmrath, MA.,Naren, AP. Drug-induced secretory Diarrhea: A role for CFTR. Pharmacol Res. 2015 Dec; 102:107-12.  (PMID-26429773).
  11. Noolu B, Gogulothu R, Bhat M, Qadri SS, Reddy VS, Reddy GB, Ismail A. In vivo inhibition of Proteasome activity and tumor growth by Murraya koenigii leaf extract in breast cancer xenografts and by its active flavonoids in breast cancer cell lines. Anticancer Agents Med Chem.  2016; 16(12):1605-1614. (PMID-27198988).

Award and recognition:
  1. JRF Award by Indian Council of Medical Research
  2. JRF and Lectureship Award by UGC
  3. SRF Award by UGC
  4. Certificate of Merit for Oral Presentation in Asia-ARVO, New Delhi. October 28-31, 2013
  5. International Travel Grant award by DST-SERB
  6. PDF award from Cincinnati Children’s Hospital Medical Center (CCHMC), Cincinnati, Ohio
  7. N-PDF award by SERB
  8. Dr.D.S. Kothari Postdoctoral fellowship award by UGC

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