National Institute of Nutrition
Jamai-Osmania PO
Hyderabad-500 007, India.
Ph No: #+914027197200
Email: ,
FAX: 04027019074

Name: Dr. P. Suryanarayana, M.Sc, PhD (Biochemistry)
Scientist  'E'
Phone: +91-40-27197414
E-mail: ;

Brief Profile:

We are mainly working on diabetes and eye diseases. Prolonged exposure to diabetes can cause various short and long term complications like diabetic cataract and retinopathy. Though there is a treatment for cataract by surgical extraction of cataract lens and insertion of intra ocular lens (IOL) and also laser surgery for retinopathy, but it is cost effective and also may cause postoperative problems. In order to overcome these problems, it is necessary to find out the other alternative approaches to prevent or delay cataract and retinopathy.
In our lab, we are trying to find out not only the possible mechanisms involved/associated with these diseases but also prevent or delay the onset and progression of cataract and retinopathy by dietary agents/ natural sources. We have screened many dietary agents/ sources that are effective in delay of diabetic cataract inn experimental animals.
Among the diabetic population, most of the patients come under type-2 diabetes. However, there are no suitable animal models to study type-2 diabetes induced eye diseases. Therefore, we are trying to establish type-2 diabetes induced cataract and retinopathy in experimental animals and also trying to develop food components for their ability to prevent diabetic complications in these animals.
Membership in professional bodies: Executive Member and Life Member of Nutrition Society of India (NSI), Society of Biological Chemists, India and Association for Research in Vision and Ophthalmology (ARVO).
Honors/ Awards: DST-BOYSCAST- Fellow at the Department of Ophthalmology, Washington University, St. Louis and Rocky Mountain Lions Eye Institute, University of Colorado University, Denver, USA during April 2008-March 2009.

Received Association for Research in Vision and Ophthalmology (ARVO) – International Travel Grant Award in 2008 at Fort Lauderdale, Florida, USA; 6Th Dr. Pratul Goswami memorial Oration, from Dr. Pratul Goswami memorial society, an integrated society for Biomedical Research & Education, Guwahati, Assam, on 16th February 2006; Young Investigator Award at 2nd SERI-ARVO Meeting on Research in Vision and Ophthalmology, during 16-20 February 2005 at Singapore.

Research Supervisor in Nutrition and Biochemistry at Osmania University, Hyderabad, India.



List of Publications:

  1. Saraswat M, Suryanarayana P, Reddy PY, Patil MA, Balakrishna N, Reddy GB. (2010) Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats. Mol Vis; 16:1525-37.

  2. Huang SP, Palla S, Ruzycki P, Varma RA, Harter T, Reddy GB, Petrash JM.(2010) Aldo-keto reductases in the eye. J Ophthalmol; 2010:521204.

  3. Muthenna P, Suryanarayana P, Gunda SK, Petrash JM, Reddy GB. (2009) Inhibition of aldose reductase by dietary antioxidant curcumin: mechanism of inhibition, specificity and significance. FEBS Lett;583(22):3637-42.

  4. Saraswat M, Muthenna P, Suryanarayana P, Petrash JM, Reddy GB. (2008) Dietary sources of aldose reductase inhibitors: prospects for alleviating diabetic complications. Asia Pac J Clin Nutr;17(4):558-65.

  5. Suryanarayana P, Satyanarayana A, Balakrishna N, Kumar PU, Reddy GB. (2007) Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat. Med Sci Monit; 12:BR286-92.

  6. Suryanarayana P, Saraswat M, Petrash JM, Reddy GB. (2007) Emblica officinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats. Mol Vis; 13:1291-7.

  7. Mrudula T, Suryanarayana P, Srinivas PN, Reddy GB. (2007) Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. Biochem Biophys Res Commun;361(2):528-32.

  8. Raju TN, Kumar CS, Kanth VR, Ramana BV, Reddy PU, Suryanarayana P, Reddy GB. (2006) Cumulative antioxidant defense against oxidative challenge in galactose-induced cataractogenesis in Wistar rats. Indian J Exp Biol; 44(9):733-9.

  9. Sivakumar B, Nair KM, Sreeramulu D, Suryanarayana P, Ravinder P, Shatrugna V, Kumar PA, Raghunath M, Rao VV, Balakrishna N, Kumar PU, Raghuramulu N. (2006) Effect of micronutrient supplement on health and nutritional status of schoolchildren: biochemical status. Nutrition; 22(1 Suppl):S15-25.

  10. Kumar PA, Haseeb A, Suryanarayana P, Ehtesham NZ, Reddy GB. (2005) Elevated expression of alphaA- and alphaB-crystallins in streptozotocin-induced diabetic rat. Arch Biochem Biophys; 444(2):77-83.

  11. Kumar PA, Suryanarayana P, Reddy PY, Reddy GB. (2005) Modulation of alpha-crystallin chaperone activity in diabetic rat lens by curcumin. Mol Vis; 11:561-8.

  12. Suryanarayana P, Saraswat M, Mrudula T, Krishna TP, Krishnaswamy K, Reddy GB. (2005) Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats. Invest Ophthalmol Vis Sci; 46(6):2092-9.

  13. Suryanarayana P, Kumar PA, Saraswat M, Petrash JM, Reddy GB. (2004) Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract. Mol Vis. 2004; 10:148-54.
  14. Suryanarayana P, Krishnaswamy K, Reddy GB. (2003) Effect of curcumin on galactose-induced cataractogenesis in rats. Mol Vis; 9:223-30.

  15. Reddy GB, Reddy PY, Vijayalakshmi A, Kumar MS, Suryanarayana P, Sesikeran B. (2002) Effect of long-term dietary manipulation on the aggregation of rat lens crystallins: role of alpha-crystallin chaperone function. Mol Vis; 8:298-305.

  16. Reddy GB, Reddy PY, Suryanarayana P. (2001) alphaA- and alphaB-crystallins protect glucose-6-phosphate dehydrogenase against UVB irradiation-induced inactivation. Biochem Biophys Res Commun; 282(3):712-6.

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