Contact
  National Institute of Nutrition
Jamai-Osmania PO
Hyderabad-500 007, India.
Ph No: #+914027197200
Email: nin@ninindia.org ,
             nin@ap.nic.in
FAX: 04027019074
Grams: NUTRITION
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Name: DR. G. BHANUPRAKASH REDDY
Designation : Scientist ‘F’
Division: BIOCHEMISTRY
Phone: +91-40-27197252
E-mail: bhanu@icmr.org.in; geereddy@yahoo.com
 

Brief Profile:

Obtained MSc (Biochemistry) and PhD (Biochemistry) from Osmania University. Did postdoctoral research at the Indian Institute of Science, Bangalore and Case Western Reserve University, USA.Dr. Reddy’s research is focused on nutrigenomics of age-related chronic diseases: complications of diabetes and obesity, micronutrients, functional foods, geriatric nutrition, small heat shock proteins. His studies revealed a role for micronutrients in the development of diabetic complications and provided the basis for the influence of micronutrients on molecular processes involved in diabetic complications using animal models. He also identified mutations in some genes that cause age-related diseases through altered nutrition. His studies are aimed at developing suitable animal models for studying the disease biology of diabetes, prediabetes and obesity associated complications and also to understand the role of nutrition. Dr. Reddy described age-related eye diseases- retinal degeneration and cataract, in a spontaneous obese rat model. His pioneering work on involvement protein glycation and aldo-ketoreductases under chronic hyperglycemia, paved the way for exploring functional foods molecules as aldose reductase inhibitors (ARI) and antiglycating agents (AGA). Further, isolated and characterized novel compounds from functional foods as ARI and AGA for combating diabetic complications. Dr. Reddy has provided new insights into the structure, function and expression of small heat shock proteins under hyperglycemic conditions and their modulation by nutrition.

 

Total publications 150
List of Publications in the last 10 years
  1. GodiselaKK, ReddySS, KumarCU, ReddyPY, JablonskiMM, AyyagarR, ReddyGB. Impact of obesity with impaired glucose tolerance on retinal degeneration in a rat model of metabolic syndrome. Mol Vis2017; 23:263-274.
  2. SontakeV, WangY, KasamRK, ReddyGB, SinnerD, NarenAP, McCormackFX, White ES, JeggaAG, MadalaSK. Hsp90 regulation of fibroblast activation in pulmonary fibrosis. J Clin Invest-Insight 2017 Feb 23; 2(4):e91454. PMID: 28239659.
  3. ReddyGB, ReddyPY, SuroliaA. Alzheimer’s and Danish Dementia peptides induce cataract and perturb retinal architecture in rats. BioMol Concepts2017 Mar;8(1):45-84. PMID: 28222009.
  4. ReddyKA ,KuamrPU, SrinivasuluM, TriveniB, Sharada K, IsmailA, ReddyGB. Overexpression and enhanced specific activty of aldoketoreductases (AKR1B1 & AKR1B10) in human breast tumors. TheBreast 2017 February; 31:137-143. PMID: 27855345.
  5. SaravananN, PatilMA, KumarPU, SuryanarayanaP, ReddyGB. Dietary ginger improves glucose dysregulation in a long term high fat high fructose fed prediabetic rat model. Indian J ExpBiol 2017 March; 55:142-150.
  6. SivaprasadM, Shalini T, Das S, Vijayalakshmi V, ReddyGB. Vitamins B6, folic acid and B12: molecular functions and prevalence of deficiency in India. Proc Indian Natn Sci Acad Dec 2016. 82(5):1381-1394.
  7. ShaliniT, SivaprasadM, IsmailA, ReddyGB. Emerging problem of vitamin D deficiency in India. Proc Indian Natn Sci Acad Dec 2016. 82(5):1395-1412.
  8. KumarPA, ChitraPS, ReddyGB. Advanced glycationendproducts mediated cellular and molecular events in the pathology of diabetic nephropathy. BioMol Concepts2016 Dec 1;7(5-6):293-309.PMID: 27816946.
  9. ChettuSK, MadhuRB, RaoljiGB, BabuKR, RaoNSK, GopalakrishnanS, IsmailA, ReddyGB, ShafiS. First total synthesis of cyclodepsipeptidesclavatustide A and B and their enantiomers. RSC Advances. 2016. 6: 61555-61665. DOI: 10.1039/C6RA08861A.
  10. NooluB, BhatM, QadriSS, ReddyVS, ReddyGB, IsmailA. In vivo inhibition of proteasome activity and tumor growth by Murrayakoenigii leaf extract in breast cancer xenografts. Anticancer Agents Med ChemMay 20. 16, 1605-1614. PMID: 27198988.
  11. BiswasP , ChavaliVRM, AgnelloG, StoneE, ChakarovaC, DuncanJL, KannabiranC, HomsherM, BhattacharyaSS, NaeemMA, KimchiA, SharonD, IwataT, RiazuddinS,ReddyGB, HejtmancikJF, GerogiouG, RiazuddinSA, AyyagariR . A missense mutation in the ASRGL1 gene is involved in causing autosomal recessive retinal degeneration. Hum Mol Genet. 2016 Jun 15;25(12):2483-2497. PMID: 27106100.
  12. Shruthi K, Reddy SS, Reddy PY, SivalingamP, HarishankarN, ReddyGB. Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. J NutrBiochem. 2016 July. 33:73-81.PMID: 27260470.
  13. RaghuG, JakhotiaS, KuamrPA, ReddyGB. Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats. Food & Function, 2016; 7: 1574-83. PMID:26902315.
  14. YaseenR, PushpalathaH, ReddyGB, IsmaelA, AhmedA, DheyaaA, OvaisS, RathoreP, SamimM, AktharM, SharmaKC, ShafiS, SinghS, JavedK. Design and synthesis of pyridazinone substituted benzenesulfonylurea derivatives as antihyperglycaemic agents and inhibitors of aldose reductase-an enzyme embroiled in diabetic complications. J Enzyme Inhib Med Chem 2016 Dec;31(6):1415-27. PMID: 26879420.
  15. KesavanR, UpadhyayS, BendreR, ChandelS, RaghuG, RaniPU, GiriH, SahuG, KumarPU, ReddyGB,JoksicG, BeraAK, DixitM. Gentianalutea exerts anti-atherosclerotic effects by preventing endothelial inflammation and smooth muscle cell migration. NutrMetabCardiovasc Dis, 2016 Apr; 26(4):293-301. PMID: 26868432.
  16. SivaprasadM, ShaliniT, BalakrishnaN, SudarshanM, LopamudraP, SuryanarayanaP, ArlappaN, RavikumarBP, RadhikaMS, ReddyGB. Status of vitamin B12 and folate among the urban adult population in South India. Ann NutrMetab 2016; 68(2):94-102. PMID: 26667891.
  17. KumarPA, WelshG, RaghuG, SaleemM, ReddyGB. Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2:  Implications for podocyte depletion and proteinuria in diabetes. Arch BiochemBiophys2016Jan 15; 590:10-19. PMID: 26550927.
  18. Reddy VS, ReddyGB. Role ofcrystallinsdiabetic complications. BiochemBiophysActa-General Subjects 2016; 1860:269-277. PMID:25988654.
  19. DuncanJL, BiswasP, KozakI, NavaniM, SyedR, SoudryS, MenghiniM, CarusoRC, JeffreyBG, HeckenlivelyJR, ReddyGB, LeeP, RoordaA, AyyagariR. Ocular phenotype of a family with FAM161A-associated retinal degeneration.Ophthalmic Genet. 2016 Mar;37(1):44-52.PMID:25007332.
  20. KishoreTK, GanugulaR, GadeD, ReddyGB, NaginiS. Gedunin abrogates aldose reductase, PI3K/Akt/mToR and NF-kB signaling pathways to inhibit angiogenesis in a hamster model of oral carcinogenesis.Tumour Biol. 2016 Feb;37(2):2083-93. PMID: 26342697.
  21. Sontake V, Shanmukhappa SK, DiPasqualeBA, Reddy GB, Medvedovic M, Hardie WD, White ES, MadalaSK. Fibrocytes regulate Wilms Tumor 1-positive cell accumulation in severe fibrotic lung disease. J Immunol. 2015 Oct 15;195(8):3978-91; PMID: 26371248.
  22. Deshpande J, ShankaranarayananJ, BhanuprakashRG, Sreenivasa RS, Juturu V. Soluble curcumin in the prevention of diabetic retinopathy via modulation of antioxidant activity and genetic pathways – in vivo model.AdvOphthalmol Vis Syst. 2015; 3(1): 00077.
  23. ReddyGB, SivaprasadM, ShaliniT, SatyanarayanaA, SeshacharyuluM, BalakrishnaN, ViswanathK, SahayM. Plasma vitamin D status in type 2 diabetes patients with and without retinopathy. Nutrition, 2015 Jul-Aug; 31(7-8):959-63. PMID: 26059368.
  24. ReddyVS, JakhotiaS, ReddyPY, ReddyGB. Hyperglycemia induced expression, phosphorylation, and translocation of αB-crystallin in rat skeletal muscle. IUBMB Life. 2015 Apr. 67(4):291-299.PMID: 25900025.
  25. KshirsagarRP, KothamasuMV, PatilMA, NimbulkarC, ReddyGB, KumarBD, BakshiV, DiwanPV. Geranium oil ameliorates endothelial dysfunction in high-fathigh sucrosediet-induced metabolic complications in rats. J Func Foods 2015; 15:284-293.
  26. ChitraPS, SwathiT, SahayR,ReddyGB*,MenonRK, KumarPA. Growth hormone induces transforming growth factor-beta-induced protein in podocytes: Implications for podocyte depletion and proteinuria. J Cell Biochem, 2015 Sep;116(9):1947-56. PMID: 25740786.
  27. ShrivastavaS, JeengarMK, ReddyVS, ReddyGB, NaiduVG (2015).Anticancer effects of celastrol on human triple negative breast cancer: Possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways.ExpMolPathol2015; 98:313-327; PMID: 25818165.
  28. Reddy VS and Reddy GB. Emerging role for αB-crystallin as a therapeutic agent: Pros and cons. CurrMol Med 2015; 15 (1):47-61. PMID: 25601468.
  29. Snow A, Shieh B, Chang KC, Pal A, Lenhart P, Ammar D, RuzyckiP, PallaS, ReddyGB, Petrash JM. Aldose reductase expression as a risk factor for cataract. ChemBiol Interact2015June 5;234:247-253.PMID:25541468.
  30. Palika R, Mashurabad PC, Nair MK, Reddy GB, PullakhandamR. Characterization of iron binding phosphopeptide released by gastrointestinal digestion of egg white. Food Res International. 2015; 67: 308-14.
  31. JoseSS, RadhikaMS, BalakrishnaN, BrahmamGNV, ReddyGB. Development of a raw food based quantitative food frequency questionnaire and evaluation of its validity and reproducibility among urban individuals of Hyderabad, India. International J Food NutrSci 2014; 3(6): 180-187.
  32. PavithraN, SathishL, BabuN, VenkatarathanammaV, PushpalathaH, ReddyGB and AnandaK. Evaluation of α-amylase, α-glucosidase and aldose reductase inhibitors in ethyl acetate extracts of endophytic fungi isolated from anti-diabetic medicinal plants.International J PharmaceutSci Res. 2014; 5(12):5334-5341.
  33. PavithraN, SathishL, Suneel KumarA, VenkatarathanammaV, PushpalathaH, Bhanuprakash ReddyG and AnandaK. In-vitro studies on α-amylase, α-glucosidase and aldose reductase inhibitorsfound in endophytic fungi isolated from Ocimum sanctum. Current Enzyme Inhibition, 2014, 10(2), 129-136.
  34. Patil MA, Suryanarayana P, Putcha UK, SrinivasM, ReddyGB. Evaluation of neonatalstreptozotocin-induced diabetic rat model for the development of cataract. Oxid Med Cell Longev. 2014; 2014:463264. PMID: 25505935.
  35. MuthennaP, Raghu G, Kumar PA, SurekhaMV, ReddyGB. Effect of cinnamon and its procyanidin-B2 enriched fraction on diabetic nephropathy in rats. ChemBiol Interact. 2014 Sep 6; 222C:68-76. PMID: 25199697.
  36. KowshikJ, GiriH, KishoreTK, KesavanR, VankudavathRN, ReddyGB, DixitM, NaginiS. Ellagic acid inhibits VEGF/VEGFR2, PI3K/Akt and MAPK signaling cascades in the hamster cheek pouch carcinogenesis model.Anticancer Agents Med Chem. 2014; 14(9):1249-60. PMID: 25060902.
  37. ReddyVS, KumarChU, RaghuG, ReddyGB. Expression and induction of small heat shock proteins in rat heart under chronic hyperglycemic conditions. Arch BiochemBiophys. 2014 Sep 15; 558:1-9. PMID:24950024.
  38. ReddySS, ShruthiK, ReddyVS, RaghuG, SuryanarayanaP, GiridharanNV, ReddyGB. Altered ubiquitin-proteasome system leads to neuronal cell death in a spontaneous obese rat model. BiochimBiophysActa. 2014 Sep; 1840(9):2924-34. PMID: 24949983.
  39. OvaisS, PushpalathaH, ReddyGB, RathoreP, BashirR, YaseenS, DheyaaA, YaseenR, TanwarO, AktharM, SamimM, JavedK. Synthesis and biological evaluation of some new pyrazoline substituted benzenesulfonylurea/ thiourea derivatives as anti-hyperglycaemic agents and aldose reductase inhibitors.Eur J Med Chem. 2014 Jun 10; 80:209-17. PMID: 24780598.
  40. ReddyVS, KumarCU, ReddyGB. Effect of chronic hyperglycemia on crystallin levels in rat lens. BiochemBiophys Res Commun. 2014 Apr 4; 446(2):602-7. PMID: 24632206.
  41. ShrivastavaS, KulkarniP, ThummuriD, JeengarMK, NaiduVG, AlvalaM, ReddyGB, RamakrishnaS. Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells.Apoptosis. 2014 July; 19(7):1148-164. PMID: 24729100.
  42. VenkannaA, SivaB, PoornimaB, VadaparthiPR, PrasadKR, ReddyKA, ReddyGB, BabuKS. Phytochemical investigation of sesquiterpenes from the fruits of Schisandrachinensis and their cytotoxic activity. Fitoterapia. 2014 Jun; 95:102-8. PMID: 24631765.
  43. Akileshwari C, Raghu G, MuthennaP, SuryanaryanaP, Mueller NH, PetrashJM, Reddy GB. Bioflavonoid ellagic acid inhibits aldose reductase: implications for prevention of diabetic complications. 2014; J Func Foods 6: 374-383.
  44. ReddyVS, RaghuG, ReddySS, PasupulatiAK, SuryanarayanaP, ReddyGB. Response of small heat shock proteins in diabetic rat retina. InvestOphthalmol Vis Sci. 2013 Nov 19; 54(12):7674-82. PMID: 24159092.
  45. GramaCN, SuryanarayanaP, PatilMA, RaghuG, BalakrishnaN, KumarMN, ReddyGB. Efficacy of biodegradable curcumin nanoparticles in delaying cataract in diabetic rat model. PLoS One. 2013 Oct 14; 8(10):e78217. PMID: 24155984.
  46. MuthennaP, RaghuG, AkileshwariC, SinhaSN, SuryanarayanaP, ReddyGB. Inhibition of protein glycation by procyanidin-B2 enriched fraction of cinnamon: delay of diabetic cataract in rats. IUBMB Life. 2013 Nov; 65(11):941-50. PMID: 24136906.
  47. PasupulatiAK, ReddyGB. Nutrition &metabolicsyndrome. RevEndocrMetabDisord. 2013 Sep; 14(3):217. PMID: 24052338.
  48. KumarPA, ChitraPS, ReddyGB. Metabolic syndrome and associated chronic kidney diseases: nutritional interventions. Rev EndocrMetabDisord. 2013 Sep; 14(3):273-86. PMID: 24036690.
  49. RajkumarS, VasavadaAR, PraveenMR, AnanthanR, ReddyGB, TripathiH, GanatraDA, AroraAI, PatelAR. Exploration of molecular factors impairing superoxide dismutase isoforms activity in human senile cataractous lenses. Invest Ophthalmol Vis Sci. 2013 Sep 17; 54(9):6224-33. PMID: 23970468.
  50. RaniUP, KesavanR, GanugulaR, AvaneeshT, KumarUP, ReddyGB, DixitM. Ellagic acid inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and prevents atheroma formation in streptozotocin-induced diabetic rats. J NutrBiochem. 2013 Nov; 24(11):1830-9. PMID: 23866995.
  51. ReddyPY, GiridharanNV, BalakrishnaN, ValidandiV, PullakhandamR, ReddyGB. Increased risk of cataract development in WNIN-obese rats due to accumulation of intralenticularsorbitol. IUBMB Life. 2013 May; 65(5):472-8. PMID: 23504868.
  52. BalakumarM, SaravananN, PrabhuD, ReginB, ReddyGB, MohanV, RemaM, Balasubramanyam M. Benefits of early glycemic control by insulin on sensory neuropathy and cataract in diabetic rats. Indian J Exp Biol. 2013 Jan; 51(1):56-64. PMID: 23441480.
  53. CukrasC, GaasterlandT, LeeP, GudisevaHV, ChavaliVR, PullakhandamR, MaranhaoB, EdsallL, SoaresS, ReddyGB, SievingPA, AyyagariR. Exome analysis identified a novel mutation in the RBP4 gene in a consanguineous pedigree with retinal dystrophy and developmental abnormalities.PLoS One. 2012; 7(11):e50205. PMID: 23189188.
  54. PullakhandamR, PalikaR, GhoshS, ReddyGB. Contrasting effects of type 2 and type 1 diabetes on plasma RBP4 levels: the significance of transthyretin. IUBMB Life. 2012 Dec; 64(12): 975-82. PMID: 23129325.
  55. Rao VR, Muthenna P, Shankaraiah G, Akileshwari C, Babu KH, Suresh G, Babu KS, Chandra Kumar RS, Prasad KR, Yadav PA, Petrash JM, Reddy GB*, Rao JM. Synthesis and biological evaluation of new piplartineanalogues as potent aldose reductase inhibitors (ARIs). Eur J Med Chem. 2012 Nov; 57:344-61. PMID: 23124161
  56. TiruvalluruM, AnanthathmakulaP, AyyalasomayajulaV, NappanveettilG, AyyagariR, ReddyGB. Vitamin A supplementation ameliorates obesity-associated retinal degeneration in WNIN/Ob rats. Nutrition. 2013 Jan; 29(1): 298-304. PMID: 23036575.
  57. AkileshwariC, MuthennaP, NastasijevićB, JoksićG, PetrashJM, ReddyGB. Inhibition of aldose reductase by Gentianalutea extracts. Exp Diabetes Res. 2012; 2012:147965. PMID: 22844269.
  58. PuppalaM, PonderJ, SuryanarayanaP, ReddyGB, PetrashJM, LaBarberaDV. The isolation and characterization of β-glucogallin as a novel aldose reductase inhibitor from Emblicaofficinalis. PLoS One. 2012; 7(4):e31399. PMID: 22485126.
  59. SireeshaR, LaxmiSG, MamataM, ReddyPY, GoudPU, RaoPV, ReddyGB, VishnupriyaS, Padma T. Total activity of glutathione-S-transferase (GST) and polymorphisms of GSTM1 and GSTT1 genes conferring risk for the development of age-related cataracts. Exp Eye Res. 2012 May; 98:67-74. PMID: 22446016.
  60. ReddyPY, GiridharanNV, ReddyGB. Activation of sorbitol pathway in metabolic syndrome and increased susceptibility to cataract in Wistar-Obese rats. Mol Vis. 2012; 18:495-503. PMID: 22393276.
  61. MuthennaP, Akileshwari C, SaraswatM, Bhanuprakash Reddy G. Inhibition of advanced glycation end-product formation on eye lens protein by rutin. Br J Nutr. 2012 Apr; 107(7):941-9. PMID: 21864418.
  62. Reddy GB, MuthennaP, Akileshwari C, Saraswat M, PetrashJM. Inhibition of aldose reductase and sorbitol accumulation by dietary rutin. CurrSci 2011; 101: 1191-1197.
  63. ValidandiV, ReddyVS, SrinivasPN, MuellerNH, BhagyalaxmiSG, PadmaT, PetrashJM, Reddy GB. Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataract. FEBS Lett. 2011 Dec 15; 585(24):3884-9 PMID: 22085609.
  64. SatyanarayanaA, BalakrishnaN, PitlaS, ReddyPY, MudiliS, LopamudraP, SuryanarayanaP, ViswanathK, AyyagariR, ReddyGB. Status of B-vitamins and homocysteine in diabetic retinopathy: association with vitamin-B12 deficiency and hyperhomocysteinemia. PLoS One. 2011; 6(11):e26747.PMID: 22069468.
  65. MuthennaP, AkileshwariC, ReddyGB. Ellagic acid, a new antiglycating agent: its inhibition of Nϵ-(carboxymethyl)lysine. Biochem J. 2012 Feb 15; 442(1):221-30 PMID: 22060242.
  66. SuryanarayanaP, PatilMA, ReddyGB. Insulin resistance mediated biochemical alterations in eye lens of neonatalstreptozotocin-induced diabetic rat. Indian J Exp Biol. 2011 Oct; 49(10):749-55.
  67. VasireddyV, ChavaliVR, JosephVT, KadamR, LinJH, JamisonJA, KompellaUB, ReddyGB, AyyagariR. Rescue of photoreceptor degeneration by curcumin in transgenic rats with P23H rhodopsin mutation. PLoS One. 2011; 6(6):e21193. PMID: 21738619.
  68. KumarPA, ReddyPY, SuryanarayanaP, ReddyGB. Effect of tannoids enriched fraction of Emblicaofficinalis on a-crystallin chaperone activity under hyperglycemic conditions in lens organ culture. J BiophysStructBiol 2011; 3: 24-29.
  69. MrudulaT, Ghafoorunissa, SaravananN and ReddyGB.  Effects of prenatal and postnatal dietary polyunsaturated fatty acids on retinal fatty acid composition and gene expression in adult rat. J Food SciNutr 2011; 1: 102 (doi:10.4172/2155-9600.1000102).
  70. ZablockiGJ, RuzyckiPA, OverturfMA, PallaS, ReddyGB, PetrashJM. Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens. ChemBiol Interact. 2011 May 30; 191(1-3):351-6. PMID: 21329682.
  71. SrinivasPN, PatilMA, ReddyGB. Temperature-dependent coaggregation of eye lens αB- and β-crystallins. BiochemBiophys Res Commun. 2011 Feb 18; 405(3):486-90. PMID: 21256113.
  72. SrinivasP, NarahariA, PetrashJM, SwamyMJ, ReddyGB. Importance of eye lens α-crystallinheteropolymer with 3:1 αA to αB ratio: stability, aggregation, and modifications. IUBMB Life. 2010 Sep; 62(9):693-702 PMID: 20836128.
  73. SaraswatM, SuryanarayanaP, ReddyPY, PatilMA, BalakrishnaN, ReddyGB. Antiglycating potential of Zingiberofficinalis and delay of diabetic cataract in rats. Mol Vis. 2010 Aug 10; 16:1525-37.
  74. HuangSP, PallaS, RuzyckiP, VarmaRA, HarterT, ReddyGB, PetrashJM. Aldo-ketoreductases in the eye. JOphthalmol. 2010; 2010:521204.  PMID: 20628518
  75. BhagyalaxmiSG, PadmaT, ReddyGB, ReddyKR. Association of G>A transition in exon-1 of alpha crystallin gene in age-related cataracts. Oman J Ophthalmol. 2010 Jan; 3(1):7-12. PMID: 20606865.
  76. MuthennaP, SuryanarayanaP, GundaSK, PetrashJM, ReddyGB. Inhibition of aldose reductase by dietary antioxidant curcumin: mechanism of inhibition, specificity and significance. FEBS Lett. 2009 Nov 19; 583(22):3637-42. PMID: 19850041.
  77. BhagyalaxmiSG, SrinivasP, BartonKA, KumarKR, VidyavathiM, PetrashJM, Bhanuprakash ReddyG*, Padma T*. A novel mutation (F71L) in alphaA-crystallin with defective chaperone-like function associated with age-related cataract.BiochimBiophysActa. 2009 Oct; 1792(10):974-81.
  78. KumarPA, ReddyGB. Modulation of alpha-crystallin chaperone activity: a target to prevent or delay cataract? IUBMB Life. 2009 May; 61(5):485-95.  PMID: 19391162.
  79. ReddyGB, VasireddyV, MandalMN, TiruvalluruM, WangXF, JablonskiMM, NappanveettilG, AyyagariR. A novel rat model with obesity-associated retinal degeneration.Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3456-63. PMID: 19369235.
  80. PullakhandamR, SrinivasPN, NairMK, ReddyGB. Binding and stabilization of transthyretin by curcumin.ArchBiochemBiophys. 2009 May 15; 485(2):115-9 PMID: 19268650.
  81. SaraswatM, ReddyPY, MuthennaP, ReddyGB. Prevention of non-enzymicglycation of proteins by dietary agents: prospects for alleviating diabetic complications. Br J Nutr. 2009 Jun; 101(11):1714-21.
  82. KumarPA, ReddyPY, SrinivasPN, ReddyGB. Delay of diabetic cataract in rats by the antiglycating potential of cumin through modulation of alpha-crystallin chaperone activity. J NutrBiochem. 2009 Jul; 20(7):553-62. PMID: 18789666.
  83. SaraswatM, MuthennaP, SuryanarayanaP, PetrashJM, ReddyGB. Dietary sources of aldose reductase inhibitors: prospects for alleviating diabetic complications. Asia Pac J ClinNutr. 2008; 17(4):558-65. PMID: 19114390.
  84. SuroliaI, SinhaS, SarkarDP, ReddyPY, ReddyGB, SuroliaA. Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin. PLoS One. 2008 Aug 13; 3(8):e2927. PMID: 18698348.
  85. KamarthapuV, RaoKV, SrinivasPN, ReddyGB, ReddyVD. Structural and kinetic properties of Bacillus subtilis S-adenosylmethioninesynthetase expressed in Escherichia coli. BiochimBiophysActa. 2008 Dec; 1784(12):1949-58. PMID: 18634909.
  86. SrinivasPN, ReddyPY, ReddyGB. Significance of alpha-crystallinheteropolymer with a 3:1 alphaA/alphaB ratio: chaperone-like activity, structure and hydrophobicity. Biochem J. 2008 Sep 15; 414(3):453-60. PMID: 18479247.
  87. ReddyGB, SatyanarayanaA, BalakrishnaN, AyyagariR, PadmaM, ViswanathK, PetrashJM. Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy.Mol Vis. 2008 Mar 24; 14:593-601.PMID: 18385795.
  88. Anil KumarP, Bhanuprakash ReddyG. Focus on molecules: aldose reductase. Exp Eye Res. 2007 Dec; 85(6):739-40. Review. PMID: 16997295.
  89. SuryanarayanaP, SatyanarayanaA, BalakrishnaN, KumarPU, ReddyGB. Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat. MedSciMonit. 2007 Dec; 13(12):BR286-92. PMID: 18049430.
  90. KumarPA, KumarMS, ReddyGB. Effect of glycation on alpha-crystallin structure and chaperone-like function. Biochem J. 2007 Dec 1; 408(2):251-8. PMID: 17696877.
  91. SuryanarayanaP, SaraswatM, PetrashJM, ReddyGB. Emblicaofficinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats. Mol Vis. 2007 Jul 24; 13:1291-7.
  92. MrudulaT, SuryanarayanaP, SrinivasPN, ReddyGB. Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina.BiochemBiophys Res Commun. 2007 Sep 21; 361(2):528-32. PMID: 17662242.
  93. VasireddyV, UchidaY, SalemN Jr, KimSY, MandalMN, ReddyGB, BodepudiR, AldersonNL, BrownJC, HamaH, DlugoszA, EliasPM, HolleranWM, AyyagariR. Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death.HumMol Genet. 2007; 16(5):471-82.  PMID: 17208947.

Total number of books and book chapters: 5
Books & book chapters in the last 10 years
  1. GB Reddy, PS Chitra and N Arlappa. Aging: health and nutrition in Textbook of Human Nutrition (eds: M.S. Bamji, K. Krishnaswamy& G. N. V. Brahmam) 4rdEdn, pp445-464, 2016, Oxford & IBH, New Delhi.
  2. K Krishnaswamy and GB Reddy. Water soluble vitamins-deficiency disorders in Textbook of Human Nutrition (eds: M.S. Bamji, K. Krishnaswamy& G. N. V. Brahmam) 4rdEdn, pp336-357, 2016, Oxford & IBH, New Delhi.
  3. N Lakshmaiah, AV Lakshmi and GB Reddy. Water soluble vitamins in Textbook of Human Nutrition (eds: M.S. Bamji, K. Krishnaswamy& G. N. V. Brahmam) 4rdEdn, 63-84, 2016, Oxford & IBH, New Delhi.
  4. GB Reddy and P Suryanarayana. Diabetes and diabetic complications and PhyllanthusspinPhyllanthus species: Scientific Evaluation and Medicinal Applications (eds: K. B. Hari Kumar &RamadasKuttan), pp 235-253, 2011, Taylor & Francis Group.
  5. GB Reddy and N Saravanan. Nutrition and eye diseases in Textbook of Human Nutrition (eds: M.S. Bamji, K. Krishnaswamy& GNV. Brahmam) 3rdEdn, pp 418-430, 2009, Oxford & IBH, New Delhi.

Awards and recognitions:
  1. Fellow, National Academy of Sciences, India-2006
  2. Fellow, AP Akademi of Sciences India-2012
  3. Fellow, Telangana Academy of Sciences-2015 (Founding Fellow)
  4. ICMR-Basanti Devi Amir Chand Prize-2010
  5. Scopus India Young Scientist Award (Medicine)-2008
  6. Young Scientist Award, Nutrition Society of India-1994
  7. Eminent Research Supervisor Award by Dr. KV Rao Scientific Society – 2015
  8. Gates Foundation Global Health Travel Award - 2015
  9. Research to Prevent Blindness (USA)-International Research Scholars Award-2007
  10. ICMR Dr. V. N. Patwardhan Prize-2002
  11. Prof. BK. Bachhawat International Travel Award for Young Scientist-2007
  12. DHRShort-term Fellow-2014
  13. DBT-Associateship for Young Scientists-2007
  14. ICMR International Fellow-2005
  15. Associate Editor: Journal of Food Science & Technology
  16. Subject Editor: Proceedings of National Academy of Sciences, India
  17. Member, Scientific Panel on Functional Food and Nutraceuticals, Food Safety and Standards Authority of India-FSSAI (2017-19)
  18. Regional Coordinator, Telangana Academy of Sciences (2015-)
  19. Advisor, Hyderabad Chapter, National Academy of Sciences, India (2015-)
  20. Executive Member, Nutrition Society of India (2008-12)

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